Lamin a c antibodies lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope.
Anti lamin antibody what is it.
The full protein is reported to be 664 amino acid residues in length.
Expression of drosophila lamin c is developmentally regulated.
These proteins are found in many different cell types in three different forms a b and c.
Anti lamin a antibody ab26300 at 1 µg ml lane 1.
Goat anti rabbit igg h l hrp preadsorbed at 1 5000 dilution developed using the ecl technique.
However based on bioassays it appears that the mix of antibodies in this purified polyclonal anti serum bind multiply across the large laminin molecule to an extent that its biological activities are inhibited.
It is the best among many laminin function blocking preps we have tested.
Lamin a c antibody detects endogenous levels of total full length lamin a and lamin c 70 kda as well as the small fragment of lamin a and lamin c resulting from cleavage at aspartic acid 230 28 kda.
That is cell receptor binding is markedly hindered.
Anti lamin antibodies are available from several suppliers.
Recombinant human lamin a protein at 0 01 µg secondary all lanes.
Anti lamin a c antibody e 1 is a mouse monoclonal igg 1 kappa light chain lamin a c antibody provided at 200 µg ml specific for an epitope mapping between amino acids 2 29 at the n terminus of lamin a c of human origin.
Anti lamin a c terminal antibody is suitable for use in western blot 0 1 0 2 μg ml using hela nuclear extract.
Fisher pa journal of cell science 108 pt 9.
Lamin a antibody c 3 is a mouse monoclonal igg 2b kappa light chain provided at 200 µg ml.
Analogies with vertebrate a type lamins.
Performed under reducing conditions.
These proteins are found in many different cell types in three different forms a b and c.
Interphase phosphorylation of the drosophila nuclear lamin.
Lamins a and c are alternatively spliced versions of the lmna gene.
Additionally anti lamin a c terminal antibodies are suitable for use in immunoblotting approx.
Site mapping using a monoclonal antibody.
Specific for an epitope mapping between amino acids 580 601 near the c terminus of lamin a of human origin.
Weber k journal of cell science 108 pt 10.
Recombinant human lamin a protein at 0 1 µg lane 2.
Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope.
Species predicted to react based on 100 sequence homology.
